Helicobacter pylori Coinfection Is Associated With Decreased Markers of Immune Activation in ART-Naive HIV-Positive and in HIV-Negative Individuals in Ghana.
Identifieur interne : 000325 ( Main/Exploration ); précédent : 000324; suivant : 000326Helicobacter pylori Coinfection Is Associated With Decreased Markers of Immune Activation in ART-Naive HIV-Positive and in HIV-Negative Individuals in Ghana.
Auteurs : Kirsten Alexandra Eberhardt [Allemagne] ; Fred Stephen Sarfo [Ghana] ; Albert Dompreh [Ghana] ; Edmund Osei Kuffour ; Christof Geldmacher [Allemagne] ; Mareike Soltau [Allemagne] ; Marei Schachscheider [Allemagne] ; Jan Felix Drexler ; Anna Maria Eis-Hübinger ; Dieter H Ussinger ; George Bedu-Addo [Ghana] ; Richard Odame Phillips [Ghana] ; Betty Norman [Ghana] ; Gerd Dieter Burchard [Allemagne] ; Torsten FeldtSource :
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [ 1537-6591 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Co-infection (anatomopathologie), Femelle, Ghana, Humains, Infections à Helicobacter (), Infections à Helicobacter (anatomopathologie), Infections à VIH (), Infections à VIH (anatomopathologie), Jeune adulte, Lymphocytes T CD4+ (), Lymphocytes T CD4+ (immunologie), Marqueurs biologiques, Mâle, Sous-populations de lymphocytes T (), Sous-populations de lymphocytes T (immunologie), Études transversales.
- MESH :
- anatomopathologie : Co-infection, Infections à Helicobacter, Infections à VIH.
- immunologie : Lymphocytes T CD4+, Sous-populations de lymphocytes T.
- Adulte, Adulte d'âge moyen, Femelle, Ghana, Humains, Infections à Helicobacter, Infections à VIH, Jeune adulte, Lymphocytes T CD4+, Marqueurs biologiques, Mâle, Sous-populations de lymphocytes T, Études transversales.
- Wicri :
- geographic : Ghana.
English descriptors
- KwdEn :
- Adult, Biomarkers, CD4-Positive T-Lymphocytes (chemistry), CD4-Positive T-Lymphocytes (immunology), Coinfection (pathology), Cross-Sectional Studies, Female, Ghana, HIV Infections (complications), HIV Infections (pathology), Helicobacter Infections (complications), Helicobacter Infections (pathology), Humans, Male, Middle Aged, T-Lymphocyte Subsets (chemistry), T-Lymphocyte Subsets (immunology), Young Adult.
- MESH :
- chemical : Biomarkers.
- geographic : Ghana.
- chemistry : CD4-Positive T-Lymphocytes, T-Lymphocyte Subsets.
- complications : HIV Infections, Helicobacter Infections.
- immunology : CD4-Positive T-Lymphocytes, T-Lymphocyte Subsets.
- pathology : Coinfection, HIV Infections, Helicobacter Infections.
- Adult, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Young Adult.
Abstract
Helicobacter pylori coinfection in human immunodeficiency virus (HIV) patients has been associated with higher CD4+ cell counts and lower HIV-1 viral loads, with the underlying mechanisms being unknown. The objective of this study was to investigate the impact of H. pylori infection on markers of T-cell activation in HIV-positive and HIV-negative individuals.
DOI: 10.1093/cid/civ577
PubMed: 26195015
Affiliations:
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Le document en format XML
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xml:lang="fr">Allemagne</country><wicri:regionArea>Clinical Research Unit, Bernhard Nocht Institute for Tropical Medicine, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Sarfo, Fred Stephen" sort="Sarfo, Fred Stephen" uniqKey="Sarfo F" first="Fred Stephen" last="Sarfo">Fred Stephen Sarfo</name><affiliation wicri:level="1"><nlm:affiliation>Kwame Nkrumah University of Science and Technology Komfo Anokye Teaching Hospital, Kumasi, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Kwame Nkrumah University of Science and Technology Komfo Anokye Teaching Hospital, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author><author><name sortKey="Dompreh, Albert" sort="Dompreh, Albert" uniqKey="Dompreh A" first="Albert" last="Dompreh">Albert Dompreh</name><affiliation wicri:level="1"><nlm:affiliation>Komfo Anokye Teaching Hospital, Kumasi, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Komfo Anokye Teaching Hospital, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author><author><name sortKey="Kuffour, Edmund Osei" sort="Kuffour, Edmund Osei" uniqKey="Kuffour E" first="Edmund Osei" last="Kuffour">Edmund Osei Kuffour</name><affiliation><nlm:affiliation>Clinic of Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University Düsseldorf.</nlm:affiliation><wicri:noCountry code="subField">Heinrich Heine University Düsseldorf</wicri:noCountry></affiliation></author><author><name sortKey="Geldmacher, Christof" sort="Geldmacher, Christof" uniqKey="Geldmacher C" first="Christof" last="Geldmacher">Christof Geldmacher</name><affiliation wicri:level="3"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine, Medical Center of the University of Munich (Ludwig Maximilian University [LMU]) German Centre for Infection Research (partner site), Munich.</nlm:affiliation><country>Allemagne</country><placeName><settlement type="city">Munich</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region></placeName><wicri:orgArea>Division of Infectious Diseases and Tropical Medicine, Medical Center of the University of Munich (Ludwig Maximilian University [LMU]) German Centre for Infection Research (partner site)</wicri:orgArea></affiliation></author><author><name sortKey="Soltau, Mareike" sort="Soltau, Mareike" uniqKey="Soltau M" first="Mareike" last="Soltau">Mareike Soltau</name><affiliation wicri:level="3"><nlm:affiliation>Clinical Research Unit, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Clinical Research Unit, Bernhard Nocht Institute for Tropical Medicine, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Schachscheider, Marei" sort="Schachscheider, Marei" uniqKey="Schachscheider M" first="Marei" last="Schachscheider">Marei Schachscheider</name><affiliation wicri:level="3"><nlm:affiliation>Clinical Research Unit, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Clinical Research Unit, Bernhard Nocht Institute for Tropical Medicine, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Drexler, Jan Felix" sort="Drexler, Jan Felix" uniqKey="Drexler J" first="Jan Felix" last="Drexler">Jan Felix Drexler</name><affiliation><nlm:affiliation>Institute of Virology, University of Bonn Medical Centre.</nlm:affiliation><wicri:noCountry code="subField">University of Bonn Medical Centre</wicri:noCountry></affiliation></author><author><name sortKey="Eis Hubinger, Anna Maria" sort="Eis Hubinger, Anna Maria" uniqKey="Eis Hubinger A" first="Anna Maria" last="Eis-Hübinger">Anna Maria Eis-Hübinger</name><affiliation><nlm:affiliation>Institute of Virology, University of Bonn Medical Centre.</nlm:affiliation><wicri:noCountry code="subField">University of Bonn Medical Centre</wicri:noCountry></affiliation></author><author><name sortKey="H Ussinger, Dieter" sort="H Ussinger, Dieter" uniqKey="H Ussinger D" first="Dieter" last="H Ussinger">Dieter H Ussinger</name><affiliation><nlm:affiliation>Clinic of Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University Düsseldorf.</nlm:affiliation><wicri:noCountry code="subField">Heinrich Heine University Düsseldorf</wicri:noCountry></affiliation></author><author><name sortKey="Bedu Addo, George" sort="Bedu Addo, George" uniqKey="Bedu Addo G" first="George" last="Bedu-Addo">George Bedu-Addo</name><affiliation wicri:level="1"><nlm:affiliation>Kwame Nkrumah University of Science and Technology Komfo Anokye Teaching Hospital, Kumasi, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Kwame Nkrumah University of Science and Technology Komfo Anokye Teaching Hospital, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author><author><name sortKey="Phillips, Richard Odame" sort="Phillips, Richard Odame" uniqKey="Phillips R" first="Richard Odame" last="Phillips">Richard Odame Phillips</name><affiliation wicri:level="1"><nlm:affiliation>Kwame Nkrumah University of Science and Technology Komfo Anokye Teaching Hospital, Kumasi, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Kwame Nkrumah University of Science and Technology Komfo Anokye Teaching Hospital, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author><author><name sortKey="Norman, Betty" sort="Norman, Betty" uniqKey="Norman B" first="Betty" last="Norman">Betty Norman</name><affiliation wicri:level="1"><nlm:affiliation>Kwame Nkrumah University of Science and Technology Komfo Anokye Teaching Hospital, Kumasi, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Kwame Nkrumah University of Science and Technology Komfo Anokye Teaching Hospital, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author><author><name sortKey="Burchard, Gerd Dieter" sort="Burchard, Gerd Dieter" uniqKey="Burchard G" first="Gerd Dieter" last="Burchard">Gerd Dieter Burchard</name><affiliation wicri:level="3"><nlm:affiliation>Clinical Research Unit, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany Institute for Interdisciplinary Medicine, Asklepios Klinik St Georg, Hamburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Clinical Research Unit, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany Institute for Interdisciplinary Medicine, Asklepios Klinik St Georg, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Feldt, Torsten" sort="Feldt, Torsten" uniqKey="Feldt T" first="Torsten" last="Feldt">Torsten Feldt</name><affiliation><nlm:affiliation>Clinical Research Unit, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany Clinic of Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University Düsseldorf.</nlm:affiliation><wicri:noCountry code="subField">Heinrich Heine University Düsseldorf</wicri:noCountry></affiliation></author></analytic><series><title level="j">Clinical infectious diseases : an official publication of the Infectious Diseases 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(anatomopathologie)</term><term>Femelle</term><term>Ghana</term><term>Humains</term><term>Infections à Helicobacter ()</term><term>Infections à Helicobacter (anatomopathologie)</term><term>Infections à VIH ()</term><term>Infections à VIH (anatomopathologie)</term><term>Jeune adulte</term><term>Lymphocytes T CD4+ ()</term><term>Lymphocytes T CD4+ (immunologie)</term><term>Marqueurs biologiques</term><term>Mâle</term><term>Sous-populations de lymphocytes T ()</term><term>Sous-populations de lymphocytes T (immunologie)</term><term>Études transversales</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Biomarkers</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Ghana</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Co-infection</term><term>Infections à Helicobacter</term><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>CD4-Positive T-Lymphocytes</term><term>T-Lymphocyte Subsets</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>HIV Infections</term><term>Helicobacter Infections</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Lymphocytes T CD4+</term><term>Sous-populations de lymphocytes T</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>CD4-Positive T-Lymphocytes</term><term>T-Lymphocyte Subsets</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Coinfection</term><term>HIV Infections</term><term>Helicobacter Infections</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Cross-Sectional Studies</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Ghana</term><term>Humains</term><term>Infections à Helicobacter</term><term>Infections à VIH</term><term>Jeune adulte</term><term>Lymphocytes T CD4+</term><term>Marqueurs biologiques</term><term>Mâle</term><term>Sous-populations de lymphocytes T</term><term>Études transversales</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Ghana</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Helicobacter pylori coinfection in human immunodeficiency virus (HIV) patients has been associated with higher CD4+ cell counts and lower HIV-1 viral loads, with the underlying mechanisms being unknown. The objective of this study was to investigate the impact of H. pylori infection on markers of T-cell activation in HIV-positive and HIV-negative individuals.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Ghana</li></country><region><li>Bavière</li><li>District de Haute-Bavière</li><li>Hambourg</li></region><settlement><li>Hambourg</li><li>Munich</li></settlement></list><tree><noCountry><name sortKey="Drexler, Jan Felix" sort="Drexler, Jan Felix" uniqKey="Drexler J" first="Jan Felix" last="Drexler">Jan Felix Drexler</name><name sortKey="Eis Hubinger, Anna Maria" sort="Eis Hubinger, Anna Maria" uniqKey="Eis Hubinger A" first="Anna Maria" last="Eis-Hübinger">Anna Maria Eis-Hübinger</name><name sortKey="Feldt, Torsten" sort="Feldt, Torsten" uniqKey="Feldt T" first="Torsten" last="Feldt">Torsten Feldt</name><name sortKey="H Ussinger, Dieter" sort="H Ussinger, Dieter" uniqKey="H Ussinger D" first="Dieter" last="H Ussinger">Dieter H Ussinger</name><name sortKey="Kuffour, Edmund Osei" sort="Kuffour, Edmund Osei" uniqKey="Kuffour E" first="Edmund Osei" last="Kuffour">Edmund Osei Kuffour</name></noCountry><country name="Allemagne"><region name="Hambourg"><name sortKey="Eberhardt, Kirsten Alexandra" sort="Eberhardt, Kirsten Alexandra" uniqKey="Eberhardt K" first="Kirsten Alexandra" last="Eberhardt">Kirsten Alexandra Eberhardt</name></region><name sortKey="Burchard, Gerd Dieter" sort="Burchard, Gerd Dieter" uniqKey="Burchard G" first="Gerd Dieter" last="Burchard">Gerd Dieter Burchard</name><name sortKey="Geldmacher, Christof" sort="Geldmacher, Christof" uniqKey="Geldmacher C" first="Christof" last="Geldmacher">Christof Geldmacher</name><name sortKey="Schachscheider, Marei" sort="Schachscheider, Marei" uniqKey="Schachscheider M" first="Marei" last="Schachscheider">Marei Schachscheider</name><name sortKey="Soltau, Mareike" sort="Soltau, Mareike" uniqKey="Soltau M" first="Mareike" last="Soltau">Mareike Soltau</name></country><country name="Ghana"><noRegion><name sortKey="Sarfo, Fred Stephen" sort="Sarfo, Fred Stephen" uniqKey="Sarfo F" first="Fred Stephen" last="Sarfo">Fred Stephen Sarfo</name></noRegion><name sortKey="Bedu Addo, George" sort="Bedu Addo, George" uniqKey="Bedu Addo G" first="George" last="Bedu-Addo">George Bedu-Addo</name><name sortKey="Dompreh, Albert" sort="Dompreh, Albert" uniqKey="Dompreh A" first="Albert" last="Dompreh">Albert Dompreh</name><name sortKey="Norman, Betty" sort="Norman, Betty" uniqKey="Norman B" first="Betty" last="Norman">Betty Norman</name><name sortKey="Phillips, Richard Odame" sort="Phillips, Richard Odame" uniqKey="Phillips R" first="Richard Odame" last="Phillips">Richard Odame Phillips</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|texte= Helicobacter pylori Coinfection Is Associated With Decreased Markers of Immune Activation in ART-Naive HIV-Positive and in HIV-Negative Individuals in Ghana.
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